How do cells maintain proteostasis under changing environments?
Every cell needs to correctly fold, localize and regulate thousands of proteins at once in the crowded cellular environment. How they pull this off remains, up to today, incompletely understood. We are investigating how life has evolved mechanisms that preserve proteostasis under stress conditions, and how these processes are perturbed in human disease.
Find out more about our work in the Research section.
Our lab is based in wonderful Houston at the Department of Molecular and Human Genetics (MHG) at Baylor College of Medicine and the Duncan Neurological Research Institute (NRI) at the Texas Children’s Hospital. We are also a member of the Center for Alzheimer’s and Neurodegenerative Diseases (CAND), the Therapeutic Innovation Center (THINC), and the Dan L. Duncan Comprehensive Cancer Center (DLDCCC).
Come pay us a visit!
WHERE
Steven was born and raised in Belgium, where he graduated as a bioengineer at KU Leuven. He performed his undergrad and graduate work at KU Leuven and VIB in the Verstrepen lab and Van Den Bosch lab. He moved across the pond to sunny California for a postdoc at the Gitler lab at Stanford University. Throughout all of this time, Steven has been fascinated with tandem repeats, protein aggregation / condensation, and the cellular stress response.
Steven aims to create a fun, exciting, and equitable lab environment that welcomes and empowers scientists from different backgrounds.
When not in the lab, he enjoys painting, going to art museums, throwing dinner parties, thrifting vintage clothing, traveling, and concerts.
